The Hidden Blockers Campaign

WITH ‘THE HIDDEN BLOCKERS CAMPAIGN’

— our mission is to raise awareness about LDL cholesterol which can lead to atherosclerosis, one of the leading causes of cardiovascular disease.1,2 LDL cholesterol (LDL-C) stands for low-density lipoprotein cholesterol, one of the main types of lipoprotein particles in your blood.2 Another important one is high-density lipoprotein cholesterol (HDL-C).2 These particles help transport cholesterol, a fat-like substance your body needs1,3, through your bloodstream.1,4

Cholesterol itself is vital – it supports cell structure and hormone production among other functions.3 But how it is carried matters:

  • HDL-C is often called ‘good’ because it helps remove cholesterol from the bloodstream.2,5
  • LDL-C is known as ‘bad’ because it can lead to plaque buildup in your arteries.1,2

WHY IT MATTERS? 

Persistently high LDL-C levels can lead to cholesterol deposits on the walls of your blood vessels. As a result, the blood vessel walls can become ‘calcified’ and clogged. That can lead to circulatory problems and eventually, in the worst case, heart attacks.1,2

The effect of LDL cholesterol is cumulative – it builds up slowly over many years.1 That’s why it’s important to keep levels low from an early age. Earlier intervention provides a great long-term benefit.1 Making small, healthy changes today can help protect your heart for decades to come.

REVEALING THE HIDDEN RISK: THE INSPIRATION FOR OUR CAMPAIGN

Through our campaign, The Hidden Blockers, we seek to uncover the hidden risks associated with high LDL cholesterol levels and highlight their link to cardiovascular disease.

High cholesterol – especially LDL-C – usually shows no outward symptoms.4 The optimal way to detect it is through a blood test that measures your cholesterol levels.4 That’s why regular health check-ups are so important – particularly for people at risk of cardiovascular disease. Knowing your numbers gives you and your healthcare provider a chance to act early and effectively.

Doctors often refer to the principle: “The lower the better, the sooner the better.”1 This means that the lower your LDL cholesterol is – and the sooner you reach that low level – the better for your heart.1

Impressions

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DIFFERENT PEOPLE – DIFFERENT CHOLESTEROL LEVELS.

Optimal cholesterol levels vary from person to person.

It depends, among other factors, on age and pre-existing conditions.1,6 For young and healthy adults without preexisting diseases and a low risk of cardiovascular disease, the LDL level should be below 116 mg/dl.1

DISCOVER HOW MUCH YOU KNOW ABOUT CHOLESTEROL AND
NUTRITION IN JUST 2 MINUTES!
Check your knowledge HERE!

At Daiichi Sankyo Europe, we are dedicated to raising awareness of cardiovascular disease through initiatives such as The Hidden Blockers Campaign, empowering more people to take an active role in protecting their heart health.

We encourage everyone to lead a heart-healthy life through physical activity, good nutrition and mental well-being. In addition, we encourage everyone to speak with their healthcare professionals and have their cholesterol levels checked regularly, as early detection can help identify cardiovascular risk factors before symptoms appear.

References
[1]

Mach F, et al. 2025 Focused Update of the 2019 ESC/EAS Guidelines for the management of dyslipidaemias: Developed by the task force for the management of dyslipidaemias of the European Society of Cardiology (ESC) and the European Atherosclerosis Society (EAS), European Heart Journal, 2025;46(42):4359–4378.

[2]

Mendis S, et al. Global atlas on cardiovascular disease prevention and control. World Health Organization. 2011.

Available at:
https://www.who.int/publications/i/item/9789241564373
Last Accessed August 2026.
[3]

Hill MF, Bordoni B. Hyperlipidemia. In: StatPearls. Treasure Island (FL): StatPearls Publishing. 2026.

Available at:
https://www.ncbi.nlm.nih.gov/books/NBK559182/
Last Accessed August 2026.
[4]

Tabas I, et al. Cholesterol in health and disease. J Clin Invest. 2002;110(5):583-90.

[5]

Ouimet M, et al. HDL and Reverse Cholesterol Transport. Circ Res. 2019;124(10):1505-1518.

[6]

Perk J, et al. European Guidelines:1–68.

Hidden Blockers Quiz

1. Medilineplus. Cholesterol Levels: What You Need to Know. Avaiable at: https://medlineplus.gov/cholesterollevelswhatyouneedtoknow.html. Last Accesed August, 2024; 2. Bhatt, A. Cholesterol: Understanding HDL vs. LDL, Harvard Health Publishing. 2018. Available at: https://www.health.harvard.edu/blog/understanding-cholesterol-hdl-vs-ldl-2018041213608. Last Accesed August, 2024; 3. Harvard Health Publishing. Harvard Medical School. How it’s made: Cholesterol production in your body. 2017. Available at: https://www.health.harvard.edu/heart-health/how-its-made- cholesterol-production-in-your-body. Last Accesed August, 2024; 4. Cleveland Clinic. LDL. Available at: https://Consultingahealthcareprofessionalmy.clevelandclinic.org/health/articles/24391-ldl-cholesterol. Last accessed August 2024. 5. Diab A, et al. A Heart-Healthy Diet for Cardiovascular Disease Prevention: Where Are We Now? Vasc Health Risk Manag. 2023;19:237-253; 6. Fundación Española del Corazón. Pirámide de salud. Avaiable at: https://fundaciondelcorazon.com/nutricion/piramide-de-alimentacion.html. Last Accesed August, 2024.

Mind the GAC
1. Medilineplus. Cholesterol Levels: What You Need to Know. Avaiable at: https://medlineplus.gov/cholesterollevelswhatyouneedtoknow.html. Last Accesed August, 2024; 2. Bhatt, A. Cholesterol: Understanding HDL vs. LDL, Harvard Health Publishing. 2018. Available at: https://www.health.harvard.edu/blog/understanding-cholesterol-hdl-vs-ldl-2018041213608. Last Accesed August, 2024; 3. Harvard Health Publishing. Harvard Medical School. How it’s made: Cholesterol production in your body. 2017. Available at: https://www.health.harvard.edu/heart-health/how-its-made- cholesterol-production-in-your-body. Last Accesed August, 2024; 4. Cleveland Clinic. LDL. Available at: https://Consultingahealthcareprofessionalmy.clevelandclinic.org/health/articles/24391-ldl-cholesterol. Last accessed August 2024. 5. Diab A, et al. A Heart-Healthy Diet for Cardiovascular Disease Prevention: Where Are We Now? Vasc Health Risk Manag. 2023;19:237-253; 6. Fundación Española del Corazón. Pirámide de salud. Avaiable at: https://fundaciondelcorazon.com/nutricion/piramide-de-alimentacion.html. Last Accesed August, 2024.

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